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AlphaFold - The Most Useful Thing AI Has Ever Done Teacherflix 9 ビュー • 8 月前に

The biggest problems in the world might be solved by tiny molecules unlocked using AI. Take your big idea online today with https://ve42.co/hostinger - code VE at checkout.

A huge thank you to John Jumper and Kathryn Tunyasuvunakool at Google Deepmind; and to David Baker and the Institute for Protein Design at the University of Washington for their invaluable expertise and explanations.

We’re incredibly grateful to Juanita Bagawan and Lucie Kerley at Google Deepmind, and Ian C. Haydon at the UW Institute for Protein Design for their assistance with some of the animation and imagery used in this video.

Special thanks to those at Google DeepMind Production Studios for their help interviewing John Jumper:
Director - Bernardo Resende
Director of Photography - Robert Messere
Senior Audio Technician - Perry Rogantin
Senior Production Coordinator - Sarah Ellen Morton
Studio Manager - Nicholas Duke

For more on this topic head over to our Patreon for the exclusive extended interview https://www.patreon.com/posts/patreon-with-cut-122274530?utm_medium=clipboard_copy&utm_source=copyLink&utm_campaign=postshare_creator&utm_content=join_link

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0:00 How to determine protein structures
3:50 Why are proteins so complicated?
5:34 The CASP Competition and Deep Mind
9:08 How does Alphafold work?
12:06 3 ways to get better AI
14:24 What is a Transformer in AI?
17:15 The Structure Module
18:35 Alphafold 2 wins the Nobel Prize
20:36 Designing New Proteins - RF Diffusion
22:58 The Future of AI

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Try Snatoms! A molecular modelling kit I invented where the atoms snap together.
https://ve42.co/SnatomsV

Sign up to the Veritasium newsletter for weekly science updates - https://ve42.co/Newsletter

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References and Credits:
How AI Revolutionized Protein Science, but Didn’t End It. (Jun 2024) via Quanta Magazine - https://ve42.co/airev
Jumper, J., Evans, R., Pritzel, A. et al. (Jul 2021). Highly accurate protein structure prediction with AlphaFold. Nature - https://ve42.co/alphafoldtwo
Senior, A.W., Evans, R., Jumper, J. et al. (Jan 2020). Improved protein structure prediction using potentials from deep learning. Nature - https://ve42.co/alphafold
R Zwanzig, A Szabo, B Bagchi (Jan 1992). Levinthal's paradox. PMC, National Institute of Health - https://ve42.co/levparadox
Khatib, F., DiMaio, F., Foldit Contenders Group. et al. (Sept 2011). Crystal structure of a monomeric retroviral protease solved by protein folding game players. Nature - https://ve42.co/proteinfoldingsolved
DeepMind co-founder: Gaming inspired AI breakthrough. (Dec 2020) via BBC - https://ve42.co/aibreakthrough
3Blue1Brown. (Apr 2024). Transformers (how LLMs work) explained visually | DL5 via Youtube - https://ve42.co/transformers
AlphaFold impact stories. via Deepmind Blog - https://ve42.co/foldimpact
Quanta Magazine. (Oct 2024). How AI Cracked the Protein Folding Code and Won a Nobel Prize via Youtube - https://ve42.co/proteinfolding
Looking Glass Universe. (Apr 2024). how AlphaFold *actually* works via Youtube - https://ve42.co/foldworks
Google DeepMind. (Nov 2020). AlphaFold: The making of a scientific breakthrough via Youtube - https://ve42.co/alphafoldvideo
Nobel Prize. (Dec 2024). 2024 Nobel Prize lectures in chemistry | David Baker, Demis Hassabis and John Jumper via Youtube - https://ve42.co/nobelchem
The AlphaFold2 Method Paper: A Fount of Good Ideas. (Jul 2021) via moalquraishi.wordpress - https://ve42.co/Alphafoldpaper
Why Don't We Have More Protein-Protein Drug Molecules? (Dec 2009) via Science - https://ve42.co/proteindrugmol
Data sonification. via Carla Scaletti - https://ve42.co/datasonification

Images & Video:
Available here - https://ve42.co/alphafoldvisuals

And if you want to learn more about how we have been making antivenom check out our previous video How Horses Save Humans From Snakebites - https://ve42.co/veantivenom

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Directed by Sumeet Kulkarni
Written by Sumeet Kulkarni, Derek Muller and Zoe Heron
Edited by Jack Saxon
Animated by Ivy Tello, Emma Wright, Andrew Neet and Fabio Albertelli
Illustrated by Jakub Misiek
Filmed and demos done by Sumeet Kulkarni
Additional research by Geeta Thakur, Vincent Cheng and Emilia Gyles
Produced by Sumeet Kulkarni, Derek Muller, Zoe Heron, Rob Beasley Spence and Tori Brittain
Thumbnail contributions by Ren Hurley, Peter Sheppard and Ben Powell
Additional video/photos supplied by Getty Images and Storyblocks
Music from Epidemic Sound

What Actually Happens When You Are Sick? Teacherflix 3 ビュー • 8 月前に

Offset your carbon footprint on Wren: https://www.wren.co/kurzgesagt.
For the first 200 people who sign up, Kurzgesagt will pay for the first month of your subscription!
This video was sponsored by Wren, thanks a lot for the support!

Sources & further reading:
https://sites.google.com/view/....sources-whatdoesntki

There is this idea floating around that what doesn’t kill you, makes you stronger. That surviving a disease leaves you better off. And it seems to make sense because we have all experienced this. When you go through hardship, often you come out more resilient, more ready to face a difficult situation in the future. But it turns out that sometimes, what doesn’t kill you makes you weaker.
So, what happens when you get sick?

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Is Reality Real? The Simulation Argument Teacherflix 6 ビュー • 8 月前に

Watch Part 2 on Vsauce 3: https://www.youtube.com/watch?v=3d9i_0Ty7Cg

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How To Make Friends Teacherflix 3 ビュー • 8 月前に

We want to be part of your friendship journey, so we’ve created a few things you can share with new and old friends: https://kgs.link/shop-166

Sources & further reading:
https://sites.google.com/view/sources-friendship/

Friends make life good. They provide the scaffolding that makes it not just bearable but fun. They give us a sense of meaning and purpose and are a source of security, self esteem and happiness. Almost nothing predicts how happy you will be as how connected you feel and a lack of social connection is associated with a number of diseases and a shorter life.

But maybe you have scrolled through your phone, unsure who to call to go to a movie with, to celebrate with or ask for comfort. You may realize that you don’t have enough friends and feel lonely. And it is not just you. Disconnectedness and loneliness are widespread.

Many people want more close friends but don’t know how to get them.

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Iraq Explained -- ISIS, Syria and War Teacherflix 3 ビュー • 8 月前に

Washington Monument for Kids | Learn the history behind the largest obelisk in the world Teacherflix 5 ビュー • 2 年前に

Have you ever seen, in person or in photographs, the giant obelisk in Washington, DC? This tall building at the opposite end of the reflection pool in front of the Lincoln Memorial has quite a bit of history behind it. Named after George Washington, the monument was designed by Robert Mills following a competition for designs held in 1836 by the Washington Monument Society.

The construction of the monument took place in two phases due to lack of funds, political turmoil, and uncertainty about the survival of the country. No construction took place between 1856 and 1876. During the first phase between 1848 and 1856, they constructed the first 150 feet of the monument, composed of a pile of bluestone gneiss unfinished rubble stones held together by mortar.

The remainder of the monument was constructed between 1876 and 1884. It was composed of finished marble surface stones and partially backed by finished granite stones. The difference in the shading of the monument can be seen where the construction was halted and later resumed with the marble from a different source.

Surrounding the monument on the outside perimeter are fifty American flags flying 24 hours a day on a large circle of flagpoles centered on the monument. In 2011, an earthquake in the area slightly damaged the monument with over 150 cracks. Most of the damage occurred in the pyramid section at the top. Speaking of the pyramid top, the monument was originally going to have a flat top instead.

We hope you and your student(s) enjoyed learning about George Washington Carver! If you want even more information, head over to our website and download one of our many free lesson plans, full of activities, worksheets, and more!

https://learnbright.org/lesson....s/social-studies/all

Thank you for watching and learning with us! We’re constantly releasing new content and videos, so click that “Subscribe” button and you’ll get notified.

What you will learn in this video:
0:00 Introduction to the monument
0:21 Interesting facts about the Washington Monument
1:24 History and construction of the obelisk structure
2:42 Internal and external features
3:30 What you can see from the top
4:06 Review of the facts

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*Teachers and Parents! Did you know? In addition to these great videos, we have also created a library of high quality and engaging lessons for your elementary aged student(s). Visit us and sign up for a free account, and you'll instantly have access to thousands of lesson plans, learning materials, teaching instructions, activities, and assignments that your kids will really enjoy! We hope to see you soon!

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$🤩All Fraction Tricks In One Video / Solve Fractions #shorts #fraction #artikipathshala #shortsfeed$

🤩All Fraction Tricks In One Video / Solve Fractions #shorts #fraction #artikipathshala #shortsfeed Teacherflix 5 ビュー • 2 年前に

🤩All Fraction Tricks In One Video / Solve Fractions #shortsfeed @VidyaConnection

Solve Fractions Quickly/ Fraction Simplification Tricks/ Simplification of Fractions/ simplify fractions/simplification/simplification short tricks/ simplification tricks/fraction tricks/simplifying fractions/simplification math/ fraction questions/ fraction math/fraction tricks for competitive exams/fraction addition /fraction division/ fraction multiplication/ fraction subtraction/ Simplify/addition of fractions/ subtraction of fractions/ division of fractions/ multiply fractions/ maths tricks for fast calculation/math tricks/maths tricks

Guys , In this YouTube shorts you will learn and a very easy and super fast short trick to solve fractions quickly by Arti mam.
It is a fraction simplification trick/ Basic math/Mental math/ Mind trick that every student should know. And by using this trick you can save your precious time in exams and score better marks.

YOUR QURIES :

How to simplify fractions?
What is the trick to solve fractions?
What is the fastest way to solve fractions?
What are the tricks for simplification of fractions?
What are the simplification tricks for fractions?
How to divide fractions fast?
What is the easy and fast trick to add fractions?

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👉🏻Maths Quizzes and Puzzles~ Shorts playlist : https://youtube.com/playlist?l....ist=PL0E-HIiBHSf_DFd

👉🏻Reasoning Tricks~ Shorts playlist : https://youtube.com/playlist?l....ist=PL0E-HIiBHSf-4v1

👉🏻Calculation Short Tricks~ Shorts playlist : https://youtube.com/playlist?l....ist=PL0E-HIiBHSf_jZj

👉🏻Basic Concepts~ Shorts playlist : https://youtube.com/playlist?l....ist=PL0E-HIiBHSf-WHs

👉🏻Math Facts~ Shorts playlist : https://youtube.com/playlist?l....ist=PL0E-HIiBHSf_zPd

👉🏻Algebra Tricks~ Shorts playlist : https://youtube.com/playlist?l....ist=PL0E-HIiBHSf-9Oh

👉🏻Fraction Tricks~ Shorts playlist : https://youtube.com/playlist?l....ist=PL0E-HIiBHSf8lrZ

👉🏻Shorts by Arti mam on VidyaSaa : https://youtube.com/playlist?l....ist=PLbLE1i5deSxIf9N

👉🏻Maths Videos by Arti mam on VidyaSaa : https://youtube.com/playlist?l....ist=PLbLE1i5deSxIxPs

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Where Did Zika Come From? Teacherflix 3 ビュー • 8 月前に

Viewers like you help make PBS (Thank you 😃) . Support your local PBS Member Station here: https://to.pbs.org/PBSDSDonate

Get your Audible trial here: http://audible.com/ok
Tweet this video ⇒ http://bit.ly/OKTBSzika1 Share on FB ⇒ http://bit.ly/OKTBSzikaFB
↓ More info and sources below ↓

Get yourself an awesome IOTBS shirt! http://dftba.com/besmart

Follow the latest news on Zika:
https://www.cdc.gov/zika/
http://www.who.int/emergencies/zika-virus/en/

Special thanks to the following for personal interviews about Zika outbreak:

Dr. Peter Hotez - Baylor College of Medicine
Dr. Scott Weaver - UT Medical Branch, Galveston
Dr. Nikos Vasilakis - UT Medical Branch, Galveston
Dr. Dahotra Sarkar - University of Texas at Austin
Dr. Alex Wild - University of Texas at Austin
Mustapha Debboun - Harris County Mosquito Control

References/further reading:

Malaria and Rome: A History of Malaria in Ancient Italy - Robert Sallares
http://www.worldcat.org/oclc/50747841

Sallares, Robert, and Susan Gomzi. "Biomolecular archaeology of malaria."Ancient Biomolecules 3.3 (2001): 195-213.

Sallares, Robert, Abigail Bouwman, and Cecilia Anderung. "The spread of malaria to southern Europe in antiquity: new approaches to old problems."Medical history 48.03 (2004): 311-328.

Hotez, Peter J. "Neglected Tropical Diseases in the Anthropocene: The Cases of Zika, Ebola, and Other Infections." PLoS Negl Trop Dis 10.4 (2016): e0004648.

Hotez, Peter J. "Blue marble health redux: Neglected tropical diseases and human development in the Group of 20 (G20) nations and Nigeria." PLoS Negl Trop Dis 9.7 (2015): e0003672.

Thumbnail image credits:

Aedes aegypti mosquito: CDC/ Prof. Frank Hadley Collins, Dir., Cntr. for Global Health and Infectious Diseases, Univ. of Notre Dame
Zika virus capsid: Manuel Almagro Rivas, Wikimedia Commons

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