The biggest problems in the world might be solved by tiny molecules unlocked using AI. Take your big idea online today with https://ve42.co/hostinger - code VE at checkout.

A huge thank you to John Jumper and Kathryn Tunyasuvunakool at Google Deepmind; and to David Baker and the Institute for Protein Design at the University of Washington for their invaluable expertise and explanations.

We’re incredibly grateful to Juanita Bagawan and Lucie Kerley at Google Deepmind, and Ian C. Haydon at the UW Institute for Protein Design for their assistance with some of the animation and imagery used in this video.

Special thanks to those at Google DeepMind Production Studios for their help interviewing John Jumper:
Director - Bernardo Resende
Director of Photography - Robert Messere
Senior Audio Technician - Perry Rogantin
Senior Production Coordinator - Sarah Ellen Morton
Studio Manager - Nicholas Duke

For more on this topic head over to our Patreon for the exclusive extended interview https://www.patreon.com/posts/patreon-with-cut-122274530?utm_medium=clipboard_copy&utm_source=copyLink&utm_campaign=postshare_creator&utm_content=join_link

▀▀▀
0:00 How to determine protein structures
3:50 Why are proteins so complicated?
5:34 The CASP Competition and Deep Mind
9:08 How does Alphafold work?
12:06 3 ways to get better AI
14:24 What is a Transformer in AI?
17:15 The Structure Module
18:35 Alphafold 2 wins the Nobel Prize
20:36 Designing New Proteins - RF Diffusion
22:58 The Future of AI

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Try Snatoms! A molecular modelling kit I invented where the atoms snap together.
https://ve42.co/SnatomsV

Sign up to the Veritasium newsletter for weekly science updates - https://ve42.co/Newsletter

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References and Credits:
How AI Revolutionized Protein Science, but Didn’t End It. (Jun 2024) via Quanta Magazine - https://ve42.co/airev
Jumper, J., Evans, R., Pritzel, A. et al. (Jul 2021). Highly accurate protein structure prediction with AlphaFold. Nature - https://ve42.co/alphafoldtwo
Senior, A.W., Evans, R., Jumper, J. et al. (Jan 2020). Improved protein structure prediction using potentials from deep learning. Nature - https://ve42.co/alphafold
R Zwanzig, A Szabo, B Bagchi (Jan 1992). Levinthal's paradox. PMC, National Institute of Health - https://ve42.co/levparadox
Khatib, F., DiMaio, F., Foldit Contenders Group. et al. (Sept 2011). Crystal structure of a monomeric retroviral protease solved by protein folding game players. Nature - https://ve42.co/proteinfoldingsolved
DeepMind co-founder: Gaming inspired AI breakthrough. (Dec 2020) via BBC - https://ve42.co/aibreakthrough
3Blue1Brown. (Apr 2024). Transformers (how LLMs work) explained visually | DL5 via Youtube - https://ve42.co/transformers
AlphaFold impact stories. via Deepmind Blog - https://ve42.co/foldimpact
Quanta Magazine. (Oct 2024). How AI Cracked the Protein Folding Code and Won a Nobel Prize via Youtube - https://ve42.co/proteinfolding
Looking Glass Universe. (Apr 2024). how AlphaFold *actually* works via Youtube - https://ve42.co/foldworks
Google DeepMind. (Nov 2020). AlphaFold: The making of a scientific breakthrough via Youtube - https://ve42.co/alphafoldvideo
Nobel Prize. (Dec 2024). 2024 Nobel Prize lectures in chemistry | David Baker, Demis Hassabis and John Jumper via Youtube - https://ve42.co/nobelchem
The AlphaFold2 Method Paper: A Fount of Good Ideas. (Jul 2021) via moalquraishi.wordpress - https://ve42.co/Alphafoldpaper
Why Don't We Have More Protein-Protein Drug Molecules? (Dec 2009) via Science - https://ve42.co/proteindrugmol
Data sonification. via Carla Scaletti - https://ve42.co/datasonification

Images & Video:
Available here - https://ve42.co/alphafoldvisuals

And if you want to learn more about how we have been making antivenom check out our previous video How Horses Save Humans From Snakebites - https://ve42.co/veantivenom

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Directed by Sumeet Kulkarni
Written by Sumeet Kulkarni, Derek Muller and Zoe Heron
Edited by Jack Saxon
Animated by Ivy Tello, Emma Wright, Andrew Neet and Fabio Albertelli
Illustrated by Jakub Misiek
Filmed and demos done by Sumeet Kulkarni
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Thumbnail contributions by Ren Hurley, Peter Sheppard and Ben Powell
Additional video/photos supplied by Getty Images and Storyblocks
Music from Epidemic Sound

Sources & further reading:
https://sites.google.com/view/....sources-supernovadea

Supernovae are the most powerful explosions in the universe, unleashing enough energy to outshine galaxies. We have no real metaphor for their power – if the sun were to magically go supernova it would feel like you were being hit by the energy of a nuclear explosion, every second. For weeks.
While supernovae are the engines of creation, forging the elements that enable life, they also burn sterile whole regions of galaxies. So what would happen if one hit earth?

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In which John Green teaches you about the Market Revolution. In the first half of the 19th century, the way people lived and worked in the United States changed drastically. At play was the classic (if anything in a 30-year-old nation can be called classic) American struggle between the Jeffersonian ideal of individuals sustaining themselves on small farms vs. the Hamiltonian vision of an economy based on manufacturing and trade. I'll give you one guess who won. Too late! It was Hamilton, which is why if you live in the United States, you probably live in a city and are unlikely to be a farmer. Please resist the urge to comment about this if you live in the country and/or are a farmer. Your anecdotal experience doesn't change the fact that most people live in cities. In the early 19th century, new technologies in transportation and communication helped remake the economic system of the country. Railroads and telegraphs changed the way people moved goods and information around. The long and short of it is, the Market Revolution meant that people now went somewhere to work rather than working at home. Often, that somewhere was a factory where they worked for an hourly wage rather than getting paid for the volume of goods they manufactured. This shift in the way people work has repercussions in our daily lives right down to today. Watch as John teaches you how the Market Revolution sowed the seeds of change in the way Americans thought about the roles of women, slavery, and labor rights. Also, check out high school John wearing his Academic Decathalon medals.

Hey teachers and students - Check out CommonLit's free collection of reading passages and curriculum resources to learn more about the events of this episode. As America invested in its market economy, certain transcendentalists resisted the rise of production and consumerism over individual freedoms, including Henry David Thoreau in his book Walden: https://www.commonlit.org/text....s/excerpt-from-walde
Ralph Waldo Emerson promoted transcendental values as well in his essay “Self-Reliance”: https://www.commonlit.org/text....s/excerpt-from-self-

Chapters:
Introduction: The Market Revolution 00:00
The Era of Good Feelings 1:00
New technology in transportation 1:43
Steamboats and canals 2:45
Railroads & telegraphs 3:35
Factories & interchangeable parts 4:02
The rise of modern banking 4:51
Encouraging Competition 5:37
Work & life during the Market Revolution 6:29
Westward expansion & "Manifest Destiny" 8:32
Mystery Document 10:09
Transcendentalists 11:28
Wealth disparities after the Market Revolution 11:53
Credits 13:33

Crash Course is on Patreon! You can support us directly by signing up at http://www.patreon.com/crashcourse

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In which John Green teaches you about the Protestant Reformation. Prior to the Protestant Reformation, pretty much everyone in Europe was a Roman Catholic. Not to get all "great man," but Martin Luther changed all that. Martin Luther didn't like the corruption he saw in the church, especially the sale of indulgences, so he left the church and started his own. And it caught on! And it really did kind of change the world. The changes increased literacy and education, and some even say the Protestant Reformation was the beginning of Capitalism in Europe.

Crash Course is on Patreon! You can support us directly by signing up at http://www.patreon.com/crashcourse

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The greatest common factor (also called the highest common factor) is the highest number that divides exactly into two numbers.
Forget factor trees - this method is faster and neater, and gives you a better change of success!
Another tecmath math lesson brought to you by tecmath the math mad math man!

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Ai Weiwei has been called an iconoclast, a radical, a voice for the voiceless, and was once named the most powerful artist in the world. Who is Ai Weiwei? And why is he considered one of the most renowned artists of our time?


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In which we visit artist Kate Gilmore in her Brooklyn studio and receive the assignment to Walk on It.

INSTRUCTIONS - Walk On It

1. Find a big piece of wood or board

2. Paint it heavy with a color that you love

3. Put on a fabulous pair of shoes and walk on it. When it looks cool, you're done.

4. Upload it using #theartassignment

5. Fame and glory (your work might be in a future episode)

Learn more about Kate Gilmore: www.kategilmore.com
Watch an excellent video by MOCA Cleveland: http://vimeo.com/66081903
And here's one of me talking to Kate back in 2010 when she was commissioned to create a work for the Indianapolis Museum of Art: http://youtu.be/C3PjWmUJZsM

Also mentioned:
Jackson Pollock: http://youtu.be/6cgBvpjwOGo
Lynda Benglis: http://whitney.org/WatchAndLis....ten/Artists?play_id=
Bruce Nauman: http://www.pbs.org/art21/artists/bruce-nauman
Process Art: http://www.artspace.com/magazi....ne/art_101/process_a

WEBSITE: http://www.teachertube.com Linear Functions Digital Story

Markus Hohenwarter from the School of Education at Johannes Kepler University Linz talks in his speech about the free math app GeoGebra. GeoGebra was created by global community and was started over 15 years ago with a master's thesis that wanted to join math apps for geometry and algebra in one combined tool. Today, GeoGebra is a global community of teachers and students who have already shared more than 1 million interactive open educational resources on www.geogebra.org.

The lecture was recorded on June 25, 2018 at the OCCE.2018 in Linz/Austria.

7 kabalen er endnu en god kabale, som jeg spillede meget da jeg var barn.
Den er stadig både sjov og god til at lære et kortspil godt at kende.
Jeg bruger kortspil i mange af mine værksteder, så det er godt for eleverne at lave kabaler som denne - og så er det hyggeligt.
Husk også at se min video om Urkabalen: https://www.youtube.com/watch?v=hcwg6YMXKco
Der er flere spil på min hjemmeside og her på kanalen

Jeg vil blive rigtig glad, hvis du vil følge mig på alle mine kanaler

KH Anette K
Følg mig gerne her:
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https://anettekmatematik.com/
#kabale #matematik #lærmatematik

Learn about using math with the different units used for liquid volume.

We hope you are enjoying this video! For more in-depth learning, check out Miacademy.co (https://www.parents.miacademy.co/), an online learning platform with lessons and practice games that go along with our videos. Use coupon code VIDEOSPECIAL for a discount. Good for homeschoolers, Parents, Teachers, or anyone with kids in grades K-8.

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Consider how on object's properties can make it useful in serving different purposes.

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What will Google Bard be like in 2023? Just recently, Google's AI has been updated! Let's take a look at what innovations have been added. Is the neural network much better after the introduction of Google services? Can Google Bard tell you about events on your calendar? How does AI work with Google Drive? And can Google Bard search for YouTube videos?

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Letra

Roco el hurón no está de humor,
tiene sueño y quiere descansar
mañana temprano tiene que madrugar
y sus amigos solo quieren festejar.

El león, la cebra, el tigre, la pantera
y la jirafa acaban de llegar.
Ellos quieren bailar la noche entera,
pobre Roco lo van a despertar.

Y bailan chachachá y bailan agogo
bailan tango, twist y rock and roll,
Mambo, break dance, la salsa y la rumba
bailan todos menos Roco el hurón.

Bailan chachachá y bailan agogo
bailan tango, twist y rock and roll,
Mambo, break dance, la salsa y la rumba
bailan todos menos Roco el hurón.

Roco está molesto no puede dormir
quieren que el baile llegue a su fin,
Pero el rinoceronte y el canguro
están felices y no se quieren ir.

Y bailan chachachá y bailan agogo
bailan tango, twist y rock and roll,
Mambo, break dance, la salsa y la rumba
bailan todos menos Roco el hurón.

Bailan chachachá y bailan agogo
bailan tango, twist y rock and roll,
Mambo, break dance, la salsa y la rumba
bailan todos menos Roco el hurón.

Baila Roco baila Roco baila Roco baila
Baila Roco baila Roco baila Roco baila
Baila Roco baila Roco baila Roco baila
Baila Roco baila Roco baila Roco baila

Baila che, baila Harlem shake,
baila polka, swing y merengue también,
Luego baila che, baila Harlem shake,
baila polka, swing y merengue también.

Y bailan chachachá y bailan agogo
bailan tango, twist y rock and roll,
Mambo, break dance, la salsa y la rumba
bailan todos junto a Roco el huron.

Bailan chachachá y bailan agogo
bailan tango, twist y rock and roll,
Mambo, break dance, la salsa y la rumba
bailan todos junto a Roco el huron,
bailan todos junto a Roco el huron.

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Roco El Hurón - Las Canciones del Zoo 2 | El Reino Infantil

Título: Roco el Hurón
Autor/Compositor: (Torres, Macarena)
Intérprete: Carrisongs

A simple phosphorus cycle explanation

Phosphorus is not found in the atmosphere. It is important for the production of ATP, DNA, and membrane.
Phosphorus follows a biogeochemical cycle that ensures the earth always has phosphorus and phosphate.
Substances like phosphorus, carbon, and nitrogen move from living organisms to abiotic factors This cycling from living organism to abiotic factor is a biogeochemical cycle.

Phosphorus Cycle
https://www.youtube.com/watch?v=c5KqwhX1dvk

-~-~~-~~~-~~-~-
Please watch: "Study Skills Teacher's Secret Guide to your Best Grades"
https://www.youtube.com/watch?v=f3bsg8gaSbw
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*
*
For more Life Science videos and summaries see,
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Biogeochemical Cycles - How the Earth Recycles
https://moomoomath.com/how-the....-earth-recycles-elem

Thousands of parents and educators are turning to the kids’ learning app that makes real learning truly fun. Try Kids Academy with
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Welcome our new video: Associative Property of Addition | Math | Kids Academy

Kids Academy, will help your child practice and apply basic math skills through fun puzzles and mini-games in our application.

Kids Academy will guide your little math explorer through intuitive lessons with the help of our professors. This App combines math and fun while mastering the basic Common Core Math Curriculum – math has never been so FUN until NOW.!

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Hi, watch our new stories for kids about recycling, conservation, natural resources and being a good citizen on our beautiful planet. Little ones will learn how to recycle different types of materials, protect the environment and save the Earth's resources. This is an interesting video compilation for kids about ecology, responsible consumption and developing social skills and competence. Happy viewing! Let's protect and save our planet!


00:00 Start
00:38 Recycling for kids
05:03 Saving Earth's Resources
08:06 Human, Capital & Natural Resources for Kids
12:05 Good Citizenship & Social Skills for Kids

#kidsacademy #recyclingforkids #kidsvideos #storiesforkids

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This math video tutorial discusses the process of multiplying decimals that are in the tenths and hundredths place in columns. It explains how to perform simple decimal multiplication easily.

Rounding Numbers & Decimals: https://www.youtube.com/watch?v=LGRoPAPMZhA

Adding Decimals:
https://www.youtube.com/watch?v=SKRbgU_A1VU

Subtracting Decimals:
https://www.youtube.com/watch?v=MdthGCQfC0o

Multiplying Decimals:
https://www.youtube.com/watch?v=dSFja7Jsg6c

Dividing Decimals:
https://www.youtube.com/watch?v=bHkI3hGQhZI

______________________________
Fractions - Basic Introduction:
https://www.youtube.com/watch?v=3TklZi6MeJ4

Improper Fractions to Decimals:
https://www.youtube.com/watch?v=jt6UQD08azc

Decimals to Mixed Numbers:
https://www.youtube.com/watch?v=kuxX1T8jfYg

Decimal to Percent:
https://www.youtube.com/watch?v=r5dn3s0kR3s

Percent to Fraction:
https://www.youtube.com/watch?v=5ZHccsyr_JI

_________________________________
Final Exams and Video Playlists:
https://www.video-tutor.net/

This statistics video tutorial explains how to make a histogram using a frequency distribution table.

Introduction to Statistics: https://www.youtube.com/watch?v=XZo4xyJXCak

Arithmetic, Geometric, & Harmonic Mean:
https://www.youtube.com/watch?v=6G6i8vSa8Zs

Simple Frequency Tables:
https://www.youtube.com/watch?v=lyRbCwDDnJo

Relative Frequency Distribution Table:
https://www.youtube.com/watch?v=gq3FPpm2yvA

Cumulative Relative Frequency Table:
https://www.youtube.com/watch?v=6hJGa4Zp62M

_________________________________
Dot Plots and Frequency Tables:
https://www.youtube.com/watch?v=Iu17mY1VfZU

Stem and Leaf Plots:
https://www.youtube.com/watch?v=MUCvUgGfzdo

Side By Side Stem and Leaf Plots:
https://www.youtube.com/watch?v=wkAjnGmRPVo

Histograms:
https://www.youtube.com/watch?v=AndS0RLdxtk

How To Make a Frequency Polygon:
https://www.youtube.com/watch?v=y7Wb9AjbRjo

__________________________________
Quartiles, Deciles, & Percentiles:
https://www.youtube.com/watch?v=40o82o3uNfk

Interquartile Range & Outliers:
https://www.youtube.com/watch?v=STSP8gTSdT8

Skewness & Symmetric Distribution:
https://www.youtube.com/watch?v=U0NZu6f5TMI

Sample Mean and Population Mean:
https://www.youtube.com/watch?v=cmtBUWCC-6A

Mean, Median, & Mode - Grouped Data:
https://www.youtube.com/watch?v=zjHfAhcU6kE

____________________________________
Final Exams and Video Playlists:
https://www.video-tutor.net/

Go to https://establishedtitles.com/SimpleHistory and use the Discount Code: SIMPLE10 to get 10% off to become a Lord or Lady!


An unexplained phenomenon

Outbreaks of this so-called dancing mania involved groups of people dancing erratically and uncontrollably, sometimes in their hundreds or even thousands.
Like a disease, the mania would spread from town to town and even country to country as if it were contagious.
Historical records are sometimes very detailed about these outbreaks which affected men, women, and children dancing often until they collapsed from exhaustion or injuries.


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http://www.amazon.co.uk/Daniel....-Turner/e/B00H5TYLAE


https://www.facebook.com/Simpl....e-History-5494376751

https://twitter.com/SimpleHistoryYT


Credit:
Created by Daniel Turner (B.A. (Hons) in History, University College London)

Narrator:

Chris Kane
https://vocalforge.com/